The injury occurred early in the game, and manager Mikel Arteta confirmed that Madueke was not well enough to continue playing.
Further testing has revealed that Madueke has a knee injury, which will keep him out of action for several weeks.
The timeline for his return is still unclear, but it's not believed to be a serious long-term injury, such as an ACL tear.
Arsenal has already been dealing with several injuries this season, including a knee injury to Kai Havertz and a shoulder injury to Martin Ødegaard.
These injuries have had a significant impact on the team's performance, particularly in their title challenge against Liverpool, who have a fully fit squad.
Madueke's injury may provide an opportunity for teenager Max Dowman to gain more playing time and potentially earn a spot in the first team.
Arsenal will face Newcastle United and West Ham United in the coming weeks, and the team will need to manage their injury situation to stay competitive.